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  • #16
    Originally posted by ready2go View Post
    there was a study done that showed this..The study conducted at The University of Nebraska Medical Center showed convincing evidence of a remarkable improvement in plasma uptake and bioavailability (up to 60% more soluble) of CON-CRET as compared to creatine monohydrate and all other popular forms...

    results from another study...
    •Oral bioavailability of creatine supplements is relatively low
    •Likely contributor is the low aqueous solubility of CRT relative to doses used
    •CRT HCl provides substantial improvement in aqueous solubility over other CRT supplements
    •CRT HCl has improved oral absorption compared to standard CRT mono formulation
    •Supplementation with CRT HCl provides a more efficient method for enhancing creatine levels in the body

    10 healthy subjects; each receive CRT Mono and CRT HCl; treatment order was randomly decided; 2 week washout period between treatments
    •CRT was administered (5 g Dose) with 6 fl. oz. cold water
    •Blood samples taken at, prior to, and 0.5, 1 and 2 and 3 hours after oral ingestion of creatine
    •Plasma creatine measured using HPLC

    you can see the charts here...http://www.sportsnutritionsociety.or...906_Miller.pdf

    study showed a 47% increase in plasma AUC in C HCL over CM..check it out tell me what you think.
    I'll give it a read, but I already see problems with the above. At the end of the day, compare CM to brand X in what actually matters: effects on strength, performance, or bodycomp, at equal doses, and show me wiz bang brand X was an improvements in those end points that actually matter to athletes... Beyond that, it's all mental masturbation....

    FYI:


    1. Vanakoski J, Kosunen V, Meririnne E, Seppala T. Creatine
    and caffeine in anaerobic and aerobic exercise: effects on
    physical performance and pharmacokinetic considerations. Int
    J Clin Pharmacol Ther. 1998 May;36(5):258-62.

    "Creatine was rapidly and efficiently absorbed, as reflected
    by plasma concentrations."

    2. M. Francaux, et.al. Effect of Exogenous Creatine
    Supplementation on Muscle PCr Metabolism Int J Sports Med;
    21:139-145

    "Following a single dose of creatine (5g), plasma creatine
    rises rapidly peaking one or two hours after the ingestion.
    Then it decreases to return to basal values within 8 hours
    after intake (unpublished data)."

    J Appl Physiol 1996 Jul;81(1):232-7 Muscle creatine loading
    in men. Hultman E, Soderlund K, Timmons JA, Cederblad G,
    Greenhaff PL

    The effect of dietary creatine and supplementation on
    skeletal muscle creatine accumulation and subsequent
    degradation and on urinary creatinine excretion was
    investigated in 31 male subjects who ingested creatine in
    different quantities over varying time periods. Muscle total
    creatine concentration increased by approximately 20% after
    6 days of creatine supplementation at a rate of 20 g/day.
    This elevated concentration was maintained when
    supplementation was continued at a rate of 2 g/day for a
    further 30 days. In the absence of 2 g/day supplementation,
    total creatine concentration gradually declined, such that
    30 days after the cessation of supplementation the
    concentration was no different from the presupplementation
    value. During this period, urinary creatinine excretion was
    correspondingly increased. A similar, but more gradual, 20%
    increase in muscle total creatine concentration was observed
    over a period of 28 days when supplementation was undertaken
    at a rate of 3 g/day. In conclusion, a rapid way to
    "creatine load" human skeletal muscle is to ingest 20 g of
    creatine for 6 days. This elevated tissue concentration can
    then be maintained by ingestion of 2 g/day thereafter. The
    ingestion of 3 g creatine/day is in the long term likely to
    be as effective at raising tissue levels as this higher
    dose.
    Last edited by WillBrink; 01-14-2010, 12:28 PM.
    - Will

    Performance/Fitness Advice For the Tactical Community

    www.OptimalSWAT.com

    General Performance/Fitness Advice for all

    www.BrinkZone.com

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    • #17
      interesting. i was not aware of the loading study. i never load creatine. i usually take in 10 grams a day..5g pre workout and 5g post workout.

      Comment


      • #18
        Originally posted by ready2go View Post
        interesting. i was not aware of the loading study. i never load creatine. i usually take in 10 grams a day..5g pre workout and 5g post workout.

        Pretty much all you could ever need to know on CM:

        www.Creatine-report.com

        On the above, the people who did that "study" are the same people who invented of CEE...

        They are currently in a lawsuit:

        http://www.itcblog.com/wp-content/up...dcomplaint.pdf

        There's probably nothing wrong per se with creatine hydrochloride, again,
        ultimately, the proof is in mass and strength performance, and much of what they have claimed in this study, is counter to actual published data.

        Color me not impressed....
        - Will

        Performance/Fitness Advice For the Tactical Community

        www.OptimalSWAT.com

        General Performance/Fitness Advice for all

        www.BrinkZone.com

        Comment


        • #19
          good feedback..

          i believe you may have the wrong company in that study you posted. the company for C HCL has a patent on the product and is called ProMera. the company in that study is Proviant i believe.

          Comment

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