Good weightlifting supplement?

[WillBrink]

there was a study done that showed this..The study conducted at The University of Nebraska Medical Center showed convincing evidence of a remarkable improvement in plasma uptake and bioavailability (up to 60% more soluble) of CON-CRET as compared to creatine monohydrate and all other popular forms...

results from another study...
•Oral bioavailability of creatine supplements is relatively low
•Likely contributor is the low aqueous solubility of CRT relative to doses used
•CRT HCl provides substantial improvement in aqueous solubility over other CRT supplements
•CRT HCl has improved oral absorption compared to standard CRT mono formulation
•Supplementation with CRT HCl provides a more efficient method for enhancing creatine levels in the body

10 healthy subjects; each receive CRT Mono and CRT HCl; treatment order was randomly decided; 2 week washout period between treatments
•CRT was administered (5 g Dose) with 6 fl. oz. cold water
•Blood samples taken at, prior to, and 0.5, 1 and 2 and 3 hours after oral ingestion of creatine
•Plasma creatine measured using HPLC

you can see the charts here...http://www.sportsnutritionsociety.or...906_Miller.pdf

study showed a 47% increase in plasma AUC in C HCL over CM..check it out tell me what you think.

I'll give it a read, but I already see problems with the above. At the end of the day, compare CM to brand X in what actually matters: effects on strength, performance, or bodycomp, at equal doses, and show me wiz bang brand X was an improvements in those end points that actually matter to athletes... Beyond that, it's all mental masturbation....

FYI:


1. Vanakoski J, Kosunen V, Meririnne E, Seppala T. Creatine
and caffeine in anaerobic and aerobic exercise: effects on
physical performance and pharmacokinetic considerations. Int
J Clin Pharmacol Ther. 1998 May;36(5):258-62.

"Creatine was rapidly and efficiently absorbed, as reflected
by plasma concentrations."

2. M. Francaux, et.al. Effect of Exogenous Creatine
Supplementation on Muscle PCr Metabolism Int J Sports Med;
21:139-145

"Following a single dose of creatine (5g), plasma creatine
rises rapidly peaking one or two hours after the ingestion.
Then it decreases to return to basal values within 8 hours
after intake (unpublished data)."

J Appl Physiol 1996 Jul;81(1):232-7 Muscle creatine loading
in men. Hultman E, Soderlund K, Timmons JA, Cederblad G,
Greenhaff PL

The effect of dietary creatine and supplementation on
skeletal muscle creatine accumulation and subsequent
degradation and on urinary creatinine excretion was
investigated in 31 male subjects who ingested creatine in
different quantities over varying time periods. Muscle total
creatine concentration increased by approximately 20% after
6 days of creatine supplementation at a rate of 20 g/day.
This elevated concentration was maintained when
supplementation was continued at a rate of 2 g/day for a
further 30 days. In the absence of 2 g/day supplementation,
total creatine concentration gradually declined, such that
30 days after the cessation of supplementation the
concentration was no different from the presupplementation
value. During this period, urinary creatinine excretion was
correspondingly increased. A similar, but more gradual, 20%
increase in muscle total creatine concentration was observed
over a period of 28 days when supplementation was undertaken
at a rate of 3 g/day. In conclusion, a rapid way to
"creatine load" human skeletal muscle is to ingest 20 g of
creatine for 6 days. This elevated tissue concentration can
then be maintained by ingestion of 2 g/day thereafter. The
ingestion of 3 g creatine/day is in the long term likely to
be as effective at raising tissue levels as this higher
dose.

[ready2go]

interesting. i was not aware of the loading study. i never load creatine. i usually take in 10 grams a day..5g pre workout and 5g post workout.

[WillBrink]

interesting. i was not aware of the loading study. i never load creatine. i usually take in 10 grams a day..5g pre workout and 5g post workout.

Pretty much all you could ever need to know on CM:

www.Creatine-report.com

On the above, the people who did that "study" are the same people who invented of CEE...

They are currently in a lawsuit:

http://www.itcblog.com/wp-content/up...dcomplaint.pdf

There's probably nothing wrong per se with creatine hydrochloride, again,
ultimately, the proof is in mass and strength performance, and much of what they have claimed in this study, is counter to actual published data.

Color me not impressed....

[ready2go]

good feedback..

i believe you may have the wrong company in that study you posted. the company for C HCL has a patent on the product and is called ProMera. the company in that study is Proviant i believe.